9
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10911 | H3 receptor antagonist 1 | Histamine Receptor | |
H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist. | |||
T79500 | KSK94 | Histamine Receptor | |
KSK94 is a specific H3 receptor antagonist that inhibits H3, sigma-1, and sigma-2 receptors , with Ki values of 7.9, 2958, and 75.2 nM, respectively, and can be used to study injurious pain and neuropathic pain. | |||
T79499 | KSK68 | Histamine Receptor | |
KSK68 is a potent dual sigma-1 and histamine H3 receptor antagonist with potential analgesic activity and high affinity for H3 receptors, sigma-1, sigma-2 receptors.KSK68 can be used in the study of pain related diseases... | |||
T14087 | ABT-239 | TRP/TRPV Channel | |
ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists. It also acts as a transient receptor potential vanilloid type 1 (TRPV1) antagonist. | |||
T26643 | Aplysamine-1 | Aplysamine | |
Aplysamine-1 is an antagonist of histamine H3 receptor. | |||
T60340 | ROS 234 | ||
ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibit... | |||
T78734 | Sigma-1 receptor antagonist 5 | Sigma receptor | |
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptors (Ki=4.5 nM (σ1R), 10 nM (σ2R)) and the histamine H3 receptor... | |||
T61603 | H3R antagonist 2 | ||
H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor antagonist. It exhibits inhibitory effects on acetylcholinesterase, butyrylcholinesterase, and human monoamine oxidase B (hMAO B) with IC50 values of ... | |||
T10462L | Bavisant dihydrochloride hydrate | JNJ31001074AAC | Others |
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatm... |